Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-kB signaling in neurons
نویسندگان
چکیده
Hans-Georg König, Beau J. Fenner*, Jennifer C. Byrne, Robert F. Schwamborn, Tytus Bernas, Caroline A. Jefferies and Jochen H. M. Prehn Centre for the Study of Neurological Disorders (CSND), Department of Physiology and Medical Physics, Centre for Systems Medicine (CSM), Department of Physiology and Medical Physics, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 Saint Stephen’s Green, Dublin 2, Ireland
منابع مشابه
Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons.
Neuronal survival and plasticity critically depend on constitutive activity of the transcription factor nuclear factor-κB (NF-κB). We here describe a role for a small intracellular fibroblast growth factor homologue, the fibroblast growth factor homologous factor 1 (FHF1/FGF12), in the regulation of NF-κB activity in mature neurons. FHFs have previously been described to control neuronal excita...
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تاریخ انتشار 2013